White Papers
MIRAI X CRYO Product Portfolio ‒ Process Cooling from -120⁰C to +50⁰C
This free white paper offers an overview of MIRAI INTEX's MIRAI X CRYO product range, which is designed for process cooling …
ISO 14644-1 Cleanroom-Compatible Equipment to Ensure Good Manufacturing Practice
Cleanrooms are defined as environments within which the concentration of airborne particles is controlled. They are designed and operated in …
PROTAC Building Blocks
Targeted protein degradation (TDP) has been an attractive concept in the drug discovery to selectively remove the disease-causing proteins from …
Lexitropsin Building Blocks
The naturally occurring oligopeptide antibiotics Netropsin and Distamycin not only represent important paradigms of sequence-selective DNA minor groove binders but …
Heterocyclic Building Blocks
Heterocyclic compounds are ubiquitous in nature, and the ring systems commonly appear in many drugs and natural products approved by …
Chemical Biology Building Blocks
Chemical Biology research uses the tools of chemistry and synthesis to understand biology and pathogenesis at the molecular level and …
Troubleshooting Tablet Defects in No Time
There are numerous tablet defects: chipping, picking and sticking, cracking, lamination, and capping to name a few. Lamination and capping often …
Using the STYL’One Nano Compaction Simulator to Characterise Round and Oblong Itraconazole Amorphous Solid Dispersions Tablets
Itraconazole (ITZ) is an antifungal drug commercially available as an oral solution or more commonly as 100mg capsules. It has …
Design of Experiments (DOE): An Essential Tool to Better Understand Tablet Formulations
This free white paper covers a brief overview of the steps for pharmaceutical product development under the quality by design …
Compaction Characterisation of Piroxicam Amorphous Solid Dispersions Formulations
Amorphous solid dispersions (ASDs) have been widely used to improve the bioavailability of poorly water-soluble drugs. They are comprised of high …
Radial Die Wall Pressure Measurement
Instrumented die is used to measure maximum die-wall pressure (MDP) and residual die-wall pressure (RDP) during powder compaction. This free document …
Effect of Precompression on Capping Tendency
Compaction simulators are a key technology allowing scientists to develop formulations and troubleshoot tablet defects. It means that formulation scientists or …
Rotary Tablet Press Simulation
How close is the simulation offered by MEDELPHARM's STYL'One to that of a rotary tablet press? Download this free PDF …
Assess the Impact of Your Granulation Process Parameters with The STYL’One Evo
Powder granulation is commonly used in the pharmaceutical industry to improve flowability and compactibility of powders. In this case, our …
A Fundamental Step in Your Tablet Development
Formulation development and technical transfer from lab to production can be challenging and requires a deep knowledge of your formulation. The …